Efficacy of Olanzapine and Olanzapine-Fluoxetine Combination in the Treatment of Bipolar I Depression

2003907 citationsJournal Article

Authors

Mauricio Tohen · Eli Lilly (United States)

Eduard Vieta · Universitat de Barcelona

Joseph R. Calabrese · Case Western Reserve University

Terence A. Ketter · Stanford University

Gary Sachs · Harvard University Press

Charles L. Bowden · The University of Texas Health Science Center at San Antonio

Philip B. Mitchell

Abstract

Olanzapine is more effective than placebo, and combined olanzapine-fluoxetine is more effective than olanzapine and placebo in the treatment of bipolar I depression without increased risk of developing manic symptoms.

Topics & Keywords

Bipolar Disorder and Treatment Electroconvulsive Therapy Studies Treatment of Major Depression

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Archives of General Psychiatry

Volume 60, Issue 11, pp. 1079-1079

DOI: 10.1001/archpsyc.60.11.1079

Field-Weighted Citation Impact: 36.45