Remyelination capacity of the MS brain decreases with disease chronicity

2009402 citationsJournal Article

Authors

Thomas Goldschmidt · Hertie Foundation

Jack P. Antel · Hertie Foundation

Fatima König · Hertie Foundation

W. Brück · Hertie Foundation

Tanja Kuhlmann · Hertie Foundation

Abstract

In summary, our data demonstrate that remyelination is a frequent event in early multiple sclerosis lesions. Furthermore, the anatomic localization of a lesion might influence the extent of remyelination.

Topics & Keywords

Multiple Sclerosis Research Studies RNA Research and Splicing Neurogenesis and neuroplasticity mechanisms

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Neurology

Volume 72, Issue 22, pp. 1914-1921

DOI: 10.1212/wnl.0b013e3181a8260a

Field-Weighted Citation Impact: 10.82