The rapidly expanding CRF01_AE epidemic in China is driven by multiple lineages of HIV-1 viruses introduced in the 1990s

2013199 citationsJournal Articlehybrid Open Access

Authors

Yi Feng · Chinese Center For Disease Control and Prevention

Xiang He · Chinese Center For Disease Control and Prevention

Jenny H. Hsi · Chinese Center For Disease Control and Prevention

Fan Li · Center for Disease Control

Xingguang Li · Chinese Center For Disease Control and Prevention

Quan Wang · Nankai University

Yuhua Ruan

Abstract

China's HIV-1 epidemic of sexual transmissions, was initiated by multilineages of CRF01_AE strains, in contrast to the mono-lineage epidemic of B' strain in former plasma donors and IDUs. Our study underscores the difficulty in controlling HIV-1 sexual transmission compared with parenteral transmission.

Topics & Keywords

HIV Research and Treatment HIV/AIDS drug development and treatment Herpesvirus Infections and Treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: AIDS

Volume 27, Issue 11, pp. 1793-1802

DOI: 10.1097/qad.0b013e328360db2d

Field-Weighted Citation Impact: 7.03