The MicroRNA Spectrum in 12 Body Fluids

20102,708 citationsJournal Articlebronze Open Access

Authors

Jessica A. Weber · Institute for Systems Biology

David Baxter · Institute for Systems Biology

Shile Zhang · Institute for Systems Biology

David Huang · Institute for Systems Biology

Kuo‐How Huang

Ming‐Jen Lee · National Taiwan University

David J. Galas · Institute for Systems Biology

Abstract

MicroRNAs are ubiquitous in all the body fluid types tested. Fluid type-specific miRNAs may have functional roles associated with the surrounding tissues. In addition, the changes in miRNA spectra observed in the urine samples from patients with different urothelial conditions demonstrates the potential for using concentrations of specific miRNAs in body fluids as biomarkers for detecting and monitoring various physiopathological conditions.

Topics & Keywords

Extracellular vesicles in disease MicroRNA in disease regulation Cancer-related molecular mechanisms research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Chemistry

Volume 56, Issue 11, pp. 1733-1741

DOI: 10.1373/clinchem.2010.147405

Field-Weighted Citation Impact: 32.13