Detection of microRNA Expression in Human Peripheral Blood Microvesicles

20081,439 citationsJournal Articlegold Open Access

Authors

Melissa Piper Hunter · The Ohio State University

Noura Ismail · The Ohio State University

Xiaoli Zhang · The Ohio State University

Baltazar D. Aguda · The Ohio State University

Eun Joo Lee · The Ohio State University

Lianbo Yu · The Ohio State University

Tao Xiao ·

Abstract

This study is the first to identify and define miRNA expression in circulating plasma microvesicles of normal subjects. The data generated from this study provides a basis for future studies to determine the predictive role of peripheral blood miRNA signatures in human disease and will enable the definition of the biological processes regulated by these miRNA.

Topics & Keywords

Extracellular vesicles in disease MicroRNA in disease regulation Cancer-related molecular mechanisms research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: PLoS ONE

Volume 3, Issue 11, pp. e3694-e3694

DOI: 10.1371/journal.pone.0003694

Field-Weighted Citation Impact: 26.69