Schizophrenia genetic variants are not associated with intelligence

201348 citationsJournal Articlegreen Open Access

Authors

Afke F. Terwisscha van Scheltinga · Utrecht University

S C Bakker · Utrecht University

Neeltje E.M. van Haren · Utrecht University

Eske M. Derks · University of Amsterdam

Jacobine E. Buizer‐Voskamp · University Medical Center Utrecht

Wiepke Cahn · Utrecht University

Stephan Ripke

Abstract

Our data suggest that rare and common schizophrenia-associated variants do not explain the variation in IQ in healthy subjects or in schizophrenia patients. Thus, reductions in IQ in schizophrenia patients may be secondary to other processes related to schizophrenia risk.

Topics & Keywords

Genomic variations and chromosomal abnormalities Genetic Associations and Epidemiology Congenital heart defects research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Psychological Medicine

Volume 43, Issue 12, pp. 2563-2570

DOI: 10.1017/s0033291713000196

Field-Weighted Citation Impact: 5.57