Effect of Human Rotavirus Vaccine on Severe Diarrhea in African Infants

2010908 citationsJournal Articlebronze Open Access

Authors

Shabir A. Madhi · University of the Witwatersrand

Nigel A. Cunliffe · University of Liverpool

A. Duncan Steele · World Health Organization

Desirée Witte · University of Liverpool

Mari Kirsten · University of Pretoria

Cheryl Louw · Medical Research Council

Bagrey Ngwira ·

Abstract

Human rotavirus vaccine significantly reduced the incidence of severe rotavirus gastroenteritis among African infants during the first year of life. (ClinicalTrials.gov number, NCT00241644.)

Topics & Keywords

Viral gastroenteritis research and epidemiology Hepatitis Viruses Studies and Epidemiology Viral Infections and Immunology Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 362, Issue 4, pp. 289-298

DOI: 10.1056/nejmoa0904797

Field-Weighted Citation Impact: 44.93