Echogenic Intracardiac Focus in 2nd-Trimester Fetuses with Trisomy 21: Usefulness as a US Marker

200062 citationsJournal Article

Authors

Thomas C. Winter

Amy M. Anderson · University of Washington

Kwang‐Ting Cheng · University of Washington Medical Center

Cathy A. Komarniski · QT Ultrasound (United States)

Vivienne Souter · Swedish Medical Center

Stefanie Uhrich · University of Washington

David A. Nyberg · Swedish Medical Center

Abstract

A sonographically isolated echogenic intracardiac focus (no other anomalies or markers noted on a complete genetic sonogram) was associated in our high-risk population with a 4.8-fold (95% CI: 1.8, 12.5) increase in RR for trisomy 21 (P =.002).

Topics & Keywords

Prenatal Screening and Diagnostics Fetal and Pediatric Neurological Disorders Congenital Anomalies and Fetal Surgery

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Radiology

Volume 216, Issue 2, pp. 450-456

DOI: 10.1148/radiology.216.2.r00au32450

Field-Weighted Citation Impact: 9.32