Circulating Tumor Cells: A Useful Predictor of Treatment Efficacy in Metastatic Breast Cancer

2009318 citationsJournal Articlebronze Open Access

Authors

Minetta C. Liu

Peter G. Shields · Georgetown University

Robert Warren · Georgetown University

Philip Cohen · Georgetown University

Mary Wilkinson · Georgetown University

Yvonne Ottaviano · Georgetown University

S. Rao · Georgetown University

Abstract

We provide, to our knowledge, the first evidence of a strong correlation between CTC results and radiographic disease progression in patients receiving chemotherapy or endocrine therapy for MBC. These findings support the role of CTC enumeration as an adjunct to standard methods of monitoring disease status in MBC.

Topics & Keywords

Cancer Cells and Metastasis Cancer Genomics and Diagnostics Metastasis and carcinoma case studies

UN Sustainable Development Goals

No poverty

Publication Details

Published in: Journal of Clinical Oncology

Volume 27, Issue 31, pp. 5153-5159

DOI: 10.1200/jco.2008.20.6664

Field-Weighted Citation Impact: 10.04