Cell-Free DNA Next-Generation Sequencing in Pancreatobiliary Carcinomas

2015277 citationsJournal Article

Authors

Oliver A. Zill

Claire Greene

Andrew Hendifar · Cedars-Sinai Medical Center

Abstract

Precision medicine efforts in biliary and pancreatic cancers have been frustrated by difficulties in obtaining adequate tumor tissue for next-generation sequencing. cfDNA sequencing reliably and accurately detects tumor-derived mutations, paving the way for precision oncology approaches in these deadly diseases.

Topics & Keywords

Pancreatic and Hepatic Oncology Research Cancer Genomics and Diagnostics Genetic factors in colorectal cancer

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Cancer Discovery

Volume 5, Issue 10, pp. 1040-1048

DOI: 10.1158/2159-8290.cd-15-0274

Field-Weighted Citation Impact: 13.65