Rapid Blood-Pressure Lowering in Patients with Acute Intracerebral Hemorrhage

20131,575 citationsJournal Articlebronze Open Access

Authors

Craig S. Anderson · University of Sydney

Emma Heeley · University of Sydney

Yining Huang · Peking University

Ji‐Guang Wang · Shanghai Jiao Tong University

Christian Stapf · Sorbonne Paris Cité

Candice Delcourt · University of Sydney

Richard I. Lindley ·

Abstract

In patients with intracerebral hemorrhage, intensive lowering of blood pressure did not result in a significant reduction in the rate of the primary outcome of death or severe disability. An ordinal analysis of modified Rankin scores indicated improved functional outcomes with intensive lowering of blood pressure. (Funded by the National Health and Medical Research Council of Australia; INTERACT2 ClinicalTrials.gov number, NCT00716079.).

Topics & Keywords

Intracerebral and Subarachnoid Hemorrhage Research Neurosurgical Procedures and Complications Traumatic Brain Injury and Neurovascular Disturbances

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 368, Issue 25, pp. 2355-2365

DOI: 10.1056/nejmoa1214609

Field-Weighted Citation Impact: 80.57