Design and Optimization of Coin-Shaped Microreactor Chips for PET Radiopharmaceutical Synthesis

201098 citationsJournal Articlegreen Open Access

Authors

Arkadij M. Elizarov · Siemens Healthcare (United States)

R. Michael van Dam · California Institute of Technology

Young Shik Shin · California Institute of Technology

Hartmuth C. Kolb · Siemens (United States)

Henry C. Padgett · Siemens (United States)

David Stout · University of California, Los Angeles

Jenny Shu

Abstract

The reactor has the potential to produce multiple human doses of (18)F-FDG; the most impact, however, is expected in the synthesis of PET radiopharmaceuticals that can be made only with low yields by currently available equipment.

Topics & Keywords

Innovative Microfluidic and Catalytic Techniques Innovation Microfluidic and Capillary Electrophoresis Applications Medical Imaging Techniques and Applications

UN Sustainable Development Goals

Affordable and clean energy

Publication Details

Published in: Journal of Nuclear Medicine

Volume 51, Issue 2, pp. 282-287

DOI: 10.2967/jnumed.109.065946

Field-Weighted Citation Impact: 6.71