Comprehensive Genomic Analysis Identifies Novel Subtypes and Targets of Triple-Negative Breast Cancer

20141,358 citationsJournal Articlegreen Open Access

Authors

Matthew D. Burstein · Texas Medical Center

Anna Tsimelzon · Children's Cancer Center

Graham M. Poage · The University of Texas MD Anderson Cancer Center

Kyle R. Covington · Children's Cancer Center

Alejandro Contreras · Baylor College of Medicine

Suzanne A.W. Fuqua · Children's Cancer Center

Michelle I. Savage

Abstract

There are four stable TNBC subtypes characterized by the expression of distinct molecular profiles that have distinct prognoses. These studies identify novel subtype-specific targets that can be targeted in the future for the effective treatment of TNBCs.

Topics & Keywords

Cancer Genomics and Diagnostics Breast Cancer Treatment Studies Cancer Cells and Metastasis

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Cancer Research

Volume 21, Issue 7, pp. 1688-1698

DOI: 10.1158/1078-0432.ccr-14-0432

Field-Weighted Citation Impact: 17.67