First human treatment of resistant neoplastic meningitis by intrathecal administration of MTX Plus<sup>125</sup>IUdR

200850 citationsJournal Article

Authors

Christine Rebischung

Doreen Hoffmann

Laëtitia Stefani

M. D. Desruet · Laboratoire des Sciences de l’Information et de la Communication

Kai Wang · Harvard University

S. James Adelstein · Harvard University

Xavier Artignan

François Vincent · Institute of Pharmacology

Anne‐Sophie Gauchez

Abstract

(125)IUdR treatment proved to be feasible without acute neurological toxicity and seemed to have produced a biological response. This attempt provides the basis for designing prospective clinical trials.

Topics & Keywords

Brain Metastases and Treatment Glioma Diagnosis and Treatment Lung Cancer Research Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: International Journal of Radiation Biology

Volume 84, Issue 12, pp. 1123-1129

DOI: 10.1080/09553000802395535

Field-Weighted Citation Impact: 1.71