Abnormal Regional Cerebral Blood Flow in Cognitively Normal Elderly Subjects With Hypertension

2008152 citationsJournal Articlegreen Open Access

Authors

Weiying Dai · University of California, Davis

Oscar L. López · University of California, Davis

Owen Carmichael · University of California, Davis

James T. Becker · University of California, Davis

Lewis H. Kuller · University of California, Davis

H. Michael Gach · University of California, Davis

Abstract

rCBF is affected in normal subjects with HTN, not only in the subcortical regions, but also in limbic and paralimbic structures. We hypothesize that the HTN creates a vulnerability state for the development of neurodegenerative disorders, especially Alzheimer disease.

Topics & Keywords

Cerebrovascular and Carotid Artery Diseases Dementia and Cognitive Impairment Research Neurological Disease Mechanisms and Treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Stroke

Volume 39, Issue 2, pp. 349-354

DOI: 10.1161/strokeaha.107.495457

Field-Weighted Citation Impact: 10.57