Perioperative Chemotherapy versus Surgery Alone for Resectable Gastroesophageal Cancer

20066,302 citationsJournal Article

Authors

David Cunningham · Royal Marsden Hospital

William Allum · Royal Marsden Hospital

Sally Stenning · Medical Research Council

J N Thompson · Royal Marsden Hospital

Cornelis J.�H. van de Velde · Leiden University Medical Center

M. Nicolson · Aberdeen Royal Infirmary

J.H. Scarffe ·

Abstract

In patients with operable gastric or lower esophageal adenocarcinomas, a perioperative regimen of ECF decreased tumor size and stage and significantly improved progression-free and overall survival. (Current Controlled Trials number, ISRCTN93793971 [controlled-trials.com].).

Topics & Keywords

Gastric Cancer Management and Outcomes Esophageal Cancer Research and Treatment Metastasis and carcinoma case studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 355, Issue 1, pp. 11-20

DOI: 10.1056/nejmoa055531

Field-Weighted Citation Impact: 127.88