5-Fluorouracil induces apoptosis in rat cardiocytes through intracellular oxidative stress

2012127 citationsJournal Articlegold Open Access

Authors

Monica Lamberti · Stazione Sperimentale per l'Industria delle Pelli e delle Materie Concianti

Stefania Porto · University of Naples Federico II

Monica Marra · University of Naples Federico II

Silvia Zappavigna · University of Campania "Luigi Vanvitelli"

Anna Grimaldi · University of Campania "Luigi Vanvitelli"

Daniela Feola · Stazione Sperimentale per l'Industria delle Pelli e delle Materie Concianti

Abstract

These results suggest that cardiotoxic mechanism of chemotherapy agents are different and this disclose a new scenario for prevention of this complication.

Topics & Keywords

Chemotherapy-induced organ toxicity mitigation Chemotherapy-induced cardiotoxicity and mitigation Cell death mechanisms and regulation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Experimental & Clinical Cancer Research

Volume 31, Issue 1, pp. 60-60

DOI: 10.1186/1756-9966-31-60

Field-Weighted Citation Impact: 6.86