Noninvasive MR Imaging–guided Focal Opening of the Blood-Brain Barrier in Rabbits

20011,422 citationsJournal Article

Authors

Kullervo Hynynen · Brigham and Women's Hospital

Abstract

The blood-brain barrier can be consistently opened with focused ultrasound exposures in the presence of a US contrast agent. MR imaging signal intensity changes may be useful in the detection of blood-brain barrier opening during sonication.

Topics & Keywords

Ultrasound and Hyperthermia Applications Ultrasound Imaging and Elastography Advanced MRI Techniques and Applications

Publication Details

Published in: Radiology

Volume 220, Issue 3, pp. 640-646

DOI: 10.1148/radiol.2202001804

Field-Weighted Citation Impact: 9.68

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Noninvasive MR Imaging–guided Focal Opening of the Blood-Brain Barrier in Rabbits

Authors

Abstract

Topics & Keywords

Publication Details