Gray matter N-acetyl aspartate deficits in secondary progressive but not relapsing-remitting multiple sclerosis.

200480 citationsJournal Articlegreen Open Access

Authors

Elfar Adalsteinsson · Stanford University

Annette Langer‐Gould

Ronald J Homer

Archana Rao

Edith V. Sullivan

Christiane Abbehusen Lima

Adolf Pfefferbaum

Scott W. Atlas

Abstract

The otherwise occult abnormality in supratentorial gray matter in SPMS but not RRMS may explain the more severe physical and cognitive impairments afflicting patients with SPMS that do not correlate well with visible lesion burden.

Topics & Keywords

Multiple Sclerosis Research Studies Advanced MRI Techniques and Applications RNA regulation and disease

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: PubMed

Volume 24, Issue 10, pp. 1941-5

Field-Weighted Citation Impact: 7.03