Norovirus Vaccine Against Experimental Human GII.4 Virus Illness: A Challenge Study in Healthy Adults

2014274 citationsJournal Articlebronze Open Access

Authors

David I. Bernstein · Cincinnati Children's Hospital Medical Center

Robert L. Atmar · Michael E. DeBakey VA Medical Center

G. Marshall Lyon · Emory University

John J. Treanor · University of Rochester Medical Center

W. H. Chen · University of Maryland, Baltimore

Xi Jiang · University of Cincinnati

Jan Vinjé

Abstract

Bivalent norovirus VLP vaccine reduced norovirus-related vomiting and/or diarrhea; field efficacy studies are planned. Clinical Trials Registration. NCT01609257.

Topics & Keywords

Viral gastroenteritis research and epidemiology Viral Infections and Immunology Research Virus-based gene therapy research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Journal of Infectious Diseases

Volume 211, Issue 6, pp. 870-878

DOI: 10.1093/infdis/jiu497

Field-Weighted Citation Impact: 17.94