First Identification of <i>Pseudomonas aeruginosa</i> Isolates Producing a KPC-Type Carbapenem-Hydrolyzing β-Lactamase

2007292 citationsJournal Articlegreen Open Access

Authors

María Virginia Villegas · Centro Internacional de Entrenamiento e Investigaciones Medicas

Karen Lolans · John H. Stroger, Jr. Hospital of Cook County

Adriana Correa · Centro Internacional de Entrenamiento e Investigaciones Medicas

Juan Nicolás Kattán · Centro Internacional de Entrenamiento e Investigaciones Medicas

Jaime Alberto López · Hospital Pablo Tobon Uribe

John P. Quinn · John H. Stroger, Jr. Hospital of Cook County

Abstract

In Medellin, Colombia, three Pseudomonas aeruginosa isolates with high-level carbapenem resistance (MIC>or=256 microg/ml) and an isolate of Citrobacter freundii with reduced susceptibility to imipenem produced the plasmid-mediated class A carbapenemase KPC-2. This is the first report of a KPC-type beta-lactamase identified outside of the family Enterobacteriaceae.

Topics & Keywords

Antibiotic Resistance in Bacteria Pharmaceutical and Antibiotic Environmental Impacts Bacterial biofilms and quorum sensing

UN Sustainable Development Goals

Life in Land

Publication Details

Published in: Antimicrobial Agents and Chemotherapy

Volume 51, Issue 4, pp. 1553-1555

DOI: 10.1128/aac.01405-06

Field-Weighted Citation Impact: 10.87