LncRNA DQ786243 affects Treg related CREB and Foxp3 expression in Crohn’s disease

201395 citationsJournal Articlediamond Open Access

Authors

Yu Qiao · Shanghai Jiao Tong University

Mei Huang · Shanghai Jiao Tong University

An Xu · Shanghai Jiao Tong University

Di Zhao · Shanghai Jiao Tong University

Zhi Hua Ran · Shanghai Jiao Tong University

Jun Shen · Shanghai Jiao Tong University

Abstract

DQ786243 can be related with severity of CD. It can affect the expression of CREB and Foxp3 through which regulates the function of Treg. CREB itself seems not the mediator of DQ786243 to up-regulate Foxp3. The phosphorylation of CREB might play a more important role in the process.

Topics & Keywords

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Biomedical Science

Volume 20, Issue 1, pp. 87-87

DOI: 10.1186/1423-0127-20-87

Field-Weighted Citation Impact: 1.28

Command Palette