Plasma levels of angiopoietin-1 and -2 predict cerebral malaria outcome in Central India

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Authors

Vidhan Jain · Regional Medical Research Center

Naomi W. Lucchi · Centers for Disease Control and Prevention

Nana O. Wilson · Morehouse School of Medicine

Anna J. Blackstock · Division of Parasitic Diseases and Malaria

Avinash C. Nagpal · Netaji Subhash Chandra Bose Medical College

Pradeep K. Joel · Netaji Subhash Chandra Bose Medical College

Mrigendra P. Singh

Abstract

These results suggest that at the time of admission plasma levels of ANG-2 and ratio of ANG-2/ANG-1 are clinically informative biomarkers to predict fatal CM from MM cases while they have limited usefulness in discriminating fatal CM outcomes in a pool of CM cases in endemic settings of Central India.

Topics & Keywords

Malaria Research and Control Complement system in diseases Mosquito-borne diseases and control

UN Sustainable Development Goals

Reduced inequalities

Publication Details

Published in: Malaria Journal

Volume 10, Issue 1, pp. 383-383

DOI: 10.1186/1475-2875-10-383

Field-Weighted Citation Impact: 5.96