CFTR mutations in men with congenital bilateral absence of the vas deferens (CBAVD): a systemic review and meta-analysis

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Authors

Jianmin Yu · Zhejiang Academy of Medical Sciences

Zhanghui Chen · Zhejiang Academy of Medical Sciences

Ya Ni · Zhejiang Academy of Medical Sciences

Zhongxiang Li · Zhejiang Academy of Medical Sciences

Abstract

In summary, our results demonstrate a high frequency of CFTR mutations in CBAVD patients, and these exhibit evident ethnic differences. In addition, 5T allele and 5T/(TG)12_13 may contribute to the increased risk for CBAVD, with the 5T penetrance probably being modulated by adjacent (TG)12_13.

Topics & Keywords

Cystic Fibrosis Research Advances Tracheal and airway disorders Neonatal Respiratory Health Research

Publication Details

Published in: Human Reproduction

Volume 27, Issue 1, pp. 25-35

DOI: 10.1093/humrep/der377

Field-Weighted Citation Impact: 6.98

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CFTR mutations in men with congenital bilateral absence of the vas deferens (CBAVD): a systemic review and meta-analysis

Authors

Abstract

Topics & Keywords

Publication Details