Neuropathologic features in the hippocampus and cerebellum of three older men with fragile X syndrome

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Authors

Claudia Greco · University of California Davis Medical Center

Celestine S. Navarro · University of California Davis Medical Center

Michael R. Hunsaker · University of California, Davis

Izumi Maezawa · University of California, Davis

John F Shuler · University of California, Davis

Flora Tassone · University of California Davis Medical Center

Mary E. Delany

Abstract

Significant morphologic changes in the hippocampus and cerebellum in three adult men with FXS were identified. This pattern of pathologic features supports the idea that primary defects in neuronal migration, neurogenesis and aging may underlie the neuropathology reported in FXS.

Topics & Keywords

Genetics and Neurodevelopmental Disorders Autism Spectrum Disorder Research Genomic variations and chromosomal abnormalities

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Molecular Autism

Volume 2, Issue 1, pp. 2-2

DOI: 10.1186/2040-2392-2-2

Field-Weighted Citation Impact: 6.20