Allopurinol Attenuates Left Ventricular Remodeling and Dysfunction After Experimental Myocardial Infarction

2004220 citationsJournal Article

Authors

Niels Engberding · Medizinische Hochschule Hannover

Stephan Spiekermann · Medizinische Hochschule Hannover

Arnd Schaefer · Medizinische Hochschule Hannover

André Heineke · Medizinische Hochschule Hannover

Antje Wiencke · Medizinische Hochschule Hannover

Maja Müller · Medizinische Hochschule Hannover

Martin Fuchs

Abstract

The present study reveals a novel beneficial effect of treatment with allopurinol, ie, a marked attenuation of LV remodeling processes and dysfunction after experimental MI. Allopurinol treatment therefore represents a potential novel strategy to prevent LV remodeling and dysfunction after MI.

Topics & Keywords

Gout, Hyperuricemia, Uric Acid Cardiovascular Function and Risk Factors Cardiac Imaging and Diagnostics

Publication Details

Published in: Circulation

Volume 110, Issue 15, pp. 2175-2179

DOI: 10.1161/01.cir.0000144303.24894.1c

Field-Weighted Citation Impact: 7.57

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Allopurinol Attenuates Left Ventricular Remodeling and Dysfunction After Experimental Myocardial Infarction

Authors

Abstract

Topics & Keywords

Publication Details