Regulation, Function, and Dysregulation of Endocannabinoids in Models of Adipose and β-Pancreatic Cells and in Obesity and Hyperglycemia

2006650 citationsJournal Article

Authors

Isabel Matias

Marie‐Paule Gonthier

Pierangelo Orlando · Institute of Protein Biochemistry

Vassilis Martiadis · University of Campania "Luigi Vanvitelli"

Luciano De Petrocellis · National Research Council

Cristina Cervino · Policlinico S.Orsola-Malpighi

Stefania Petrosino

Laurence Hoareau

Franck Festy

Abstract

Peripheral endocannabinoid overactivity might explain why CB(1) blockers cause weight-loss independent reduction of lipogenesis, of hypoadiponectinemia, and of hyperinsulinemia in obese animals and humans.

Topics & Keywords

Cannabis and Cannabinoid Research Pancreatic function and diabetes Diet, Metabolism, and Disease

Publication Details

Published in: The Journal of Clinical Endocrinology & Metabolism

Volume 91, Issue 8, pp. 3171-3180

DOI: 10.1210/jc.2005-2679

Field-Weighted Citation Impact: 46.96

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Regulation, Function, and Dysregulation of Endocannabinoids in Models of Adipose and β-Pancreatic Cells and in Obesity and Hyperglycemia

Authors

Abstract

Topics & Keywords

Publication Details