Effectiveness of Antiepileptic Drug Combination Therapy for Partial-Onset Seizures Based on Mechanisms of Action

2014134 citationsJournal Article

Authors

Jay Margolis · Truven Health Analytics (United States)

Bong-Chul Chu · Truven Health Analytics (United States)

José E Cavazos · South Texas Veterans Health Care System

Abstract

The findings suggest that AED combinations with different MOAs have greater effectiveness as measured by treatment persistence and lower risks for hospitalization and emergency department visits. Further research is needed to more fully understand the role of the MOA in achieving optimal outcomes.

Topics & Keywords

Epilepsy research and treatment Pharmacological Effects and Toxicity Studies Neuroscience and Neuropharmacology Research

Publication Details

Published in: JAMA Neurology

Volume 71, Issue 8, pp. 985-985

DOI: 10.1001/jamaneurol.2014.808

Field-Weighted Citation Impact: 5.45

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Effectiveness of Antiepileptic Drug Combination Therapy for Partial-Onset Seizures Based on Mechanisms of Action

Authors

Abstract

Topics & Keywords

Publication Details