p16<sup>INK4A</sup> as a marker for cervical dyskaryosis: CIN and cGIN in cervical biopsies and ThinPrep™ smears

2002202 citationsJournal Articlebronze Open Access

Authors

Niamh Murphy · Coombe Women & Infants University Hospital

M Ring · Coombe Women & Infants University Hospital

A G Killalea · Coombe Women & Infants University Hospital

V Uhlmann · Coombe Women & Infants University Hospital

M O’Donovan · Trinity College Dublin

F Mulcahy · St. James's Hospital

M Turner · Coombe Women & Infants University Hospital

Abstract

This pattern of overexpression demonstrates the potential use of p16(INK4A) as a diagnostic marker for cervical squamous and also glandular neoplastic lesions. In addition, the technique can be used to identify individual dyskaryotic cells in ThinPrep smears. Thus, p16(INK4A) is a useful marker of cervical dyskaryosis.

Topics & Keywords

Cervical Cancer and HPV Research Cancer-related Molecular Pathways Colorectal and Anal Carcinomas

Publication Details

Published in: Journal of Clinical Pathology

Volume 56, Issue 1, pp. 56-63

DOI: 10.1136/jcp.56.1.56

Field-Weighted Citation Impact: 9.70

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p16<sup>INK4A</sup> as a marker for cervical dyskaryosis: CIN and cGIN in cervical biopsies and ThinPrep™ smears

Authors

Abstract

Topics & Keywords

Publication Details