Scan‐rescan variability in perfusion assessment of tumors in MRI using both model and data‐derived arterial input functions

The use of a data-derived AIF in the analysis of DCE-MRI data provides a substantial reduction in scan-rescan CV in the measurement of vascular parameters such as Ktrans and IAUCBN90. These results show a much larger advantage in the liver than in the lungs. However, this difference is largely driven by a small number of outliers, and may be spurious.