Diagnostic accuracy of pulmonary host inflammatory mediators in the exclusion of ventilator-acquired pneumonia

201486 citationsJournal Articlehybrid Open Access

Authors

Thomas P Hellyer · Newcastle University

Andrew Conway Morris · University of Cambridge

Daniel F. McAuley · Queen's University Belfast

Timothy Walsh · Centre for Inflammation Research

Niall Anderson · University of Edinburgh

Suveer Singh · Chelsea and Westminster Hospital

Paul Dark ·

Abstract

Low BALF IL-1β in combination with IL-8 confidently excludes VAP and could form a rapid biomarker-based rule-out test, with the potential to improve antibiotic stewardship.

Topics & Keywords

Nosocomial Infections in ICU Sepsis Diagnosis and Treatment Respiratory Support and Mechanisms

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Thorax

Volume 70, Issue 1, pp. 41-47

DOI: 10.1136/thoraxjnl-2014-205766

Field-Weighted Citation Impact: 4.48