Effects of Neuroglobin Overexpression on Acute Brain Injury and Long-Term Outcomes After Focal Cerebral Ischemia

2008149 citationsJournal Articlegreen Open Access

Authors

Xiaoying Wang · Harvard University

Jianxiang Liu · Harvard University

Haihao Zhu

Emiri Tejima · Harvard University

Kiyoshi Tsuji · Massachusetts General Hospital

Yoshihiro Murata · Harvard University

Dmitriy N. Atochin · Harvard University

Abstract

Ngb reduces tissue infarction and markers of oxidative stress after stroke. Tissue protection by overexpressing Ngb can be sustained for up to 2 weeks.

Topics & Keywords

Hemoglobin structure and function Heme Oxygenase-1 and Carbon Monoxide Erythrocyte Function and Pathophysiology

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Stroke

Volume 39, Issue 6, pp. 1869-1874

DOI: 10.1161/strokeaha.107.506022

Field-Weighted Citation Impact: 5.57