Response to Neoadjuvant Therapy and Long-Term Survival in Patients With Triple-Negative Breast Cancer

20082,876 citationsJournal Articlebronze Open Access

Authors

Cornelia Liedtke · Institut Gustave Roussy

Chafika Mazouni · The University of Texas MD Anderson Cancer Center

Kenneth R. Hess · The University of Texas MD Anderson Cancer Center

Fabrice André · The University of Texas MD Anderson Cancer Center

Attila Tordai · Institut Gustave Roussy

Jaime Mejia · The University of Texas MD Anderson Cancer Center

W. Fraser Symmans

Abstract

Patients with TNBC have increased pCR rates compared with non-TNBC, and those with pCR have excellent survival. However, patients with RD after neoadjuvant chemotherapy have significantly worse survival if they have TNBC compared with non-TNBC, particularly in the first 3 years.

Topics & Keywords

Breast Cancer Treatment Studies HER2/EGFR in Cancer Research Breast Lesions and Carcinomas

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Clinical Oncology

Volume 26, Issue 8, pp. 1275-1281

DOI: 10.1200/jco.2007.14.4147

Field-Weighted Citation Impact: 39.51