<i>DPC4</i> Gene Status of the Primary Carcinoma Correlates With Patterns of Failure in Patients With Pancreatic Cancer

20091,069 citationsJournal Articlebronze Open Access

Authors

Christine A. Iacobuzio–Donahue · Johns Hopkins University

Baojin Fu · Johns Hopkins University

Shinichi Yachida · Johns Hopkins University

Mingde Luo · Johns Hopkins University

Hisashi Abe · Johns Hopkins University

Clark M. Henderson · Johns Hopkins University

F Vilardell ·

Abstract

Pancreatic cancers are represented by distinct genetic subtypes with significantly different patterns of failure. Determinations of DPC4 status at initial diagnosis may be of value in stratifying patients into treatment regimens related to local control versus systemic therapy.

Topics & Keywords

Pancreatic and Hepatic Oncology Research Cancer Genomics and Diagnostics Neuroendocrine Tumor Research Advances

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Clinical Oncology

Volume 27, Issue 11, pp. 1806-1813

DOI: 10.1200/jco.2008.17.7188

Field-Weighted Citation Impact: 17.42