Effect of Left Ventricular Outflow Tract Obstruction on Clinical Outcome in Hypertrophic Cardiomyopathy

20031,450 citationsJournal Articlebronze Open Access

Authors

Martin S. Maron · Tufts Medical Center

Iacopo Olivotto · Azienda Ospedaliero-Universitaria Careggi

Sandro Betocchi · University of Naples Federico II

Susan A. Casey · Minneapolis Heart Institute Foundation

John R. Lesser · Minneapolis Heart Institute Foundation

Maria Angela Losi · University of Naples Federico II

Franco Cecchi

Abstract

In patients with hypertrophic cardiomyopathy, left ventricular outflow tract obstruction at rest is a strong, independent predictor of progression to severe symptoms of heart failure and of death.

Topics & Keywords

Cardiomyopathy and Myosin Studies Cardiovascular Function and Risk Factors Cardiovascular Effects of Exercise

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 348, Issue 4, pp. 295-303

DOI: 10.1056/nejmoa021332

Field-Weighted Citation Impact: 27.66