Molecular Damage in the Bronchial Epithelium of Current and Former Smokers

1997487 citationsJournal Articlebronze Open Access

Authors

Ignacio I. Wistuba

A K Virmani · Southwestern Medical Center

Adi F. Gazdar · Southwestern Medical Center

Alfred K. Lam · University of British Columbia

Jean LeRiche · University of British Columbia

Carmen Behrens · Johns Hopkins University

Kwun M. Fong · Johns Hopkins University

Abstract

Genetic changes similar to those found in lung cancers can be detected in the nonmalignant bronchial epithelium of current and former smokers and may persist for many years after smoking cessation.

Topics & Keywords

Genetic factors in colorectal cancer Cancer Genomics and Diagnostics Lung Cancer Treatments and Mutations

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JNCI Journal of the National Cancer Institute

Volume 89, Issue 18, pp. 1366-1373

DOI: 10.1093/jnci/89.18.1366

Field-Weighted Citation Impact: 20.85