A microbiological assessment of novel nitrofuranylamides as anti-tuberculosis agents

2008106 citationsJournal Articlegreen Open Access

Authors

Julian G. Hurdle · University of Tennessee Health Science Center

Robin B. Lee · University of Tennessee Health Science Center

Nageshwar Budha · University of Tennessee Health Science Center

Elizabeth I. Carson · University of Tennessee Health Science Center

Jianjun Qi · University of Tennessee Health Science Center

Michaël Scherman · Colorado State University

Sang‐Hyun Cho

Abstract

Based on these studies, NFAs have many useful antimycobacterial properties applicable to TB chemotherapy and probably possess a unique mode of action that results in good activity against active and dormant M. tuberculosis. Therefore, the further development of lead compounds in this series is warranted.

Topics & Keywords

Tuberculosis Research and Epidemiology Mycobacterium research and diagnosis Cancer therapeutics and mechanisms

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Antimicrobial Chemotherapy

Volume 62, Issue 5, pp. 1037-1045

DOI: 10.1093/jac/dkn307

Field-Weighted Citation Impact: 4.70