Docetaxel plus Prednisone or Mitoxantrone plus Prednisone for Advanced Prostate Cancer

20045,698 citationsJournal Article

Authors

Ian F. Tannock · University of Toronto

Ronald de Wit

William R. Berry

J Horti · National Institute of Oncology

A Płużańska · Medical University of Lodz

Kim N. · BC Cancer Agency

Stéphane Oudard · Hôpital Européen Georges-Pompidou

Christine Théodore ·

Abstract

When given with prednisone, treatment with docetaxel every three weeks led to superior survival and improved rates of response in terms of pain, serum PSA level, and quality of life, as compared with mitoxantrone plus prednisone.

Topics & Keywords

Prostate Cancer Treatment and Research Prostate Cancer Diagnosis and Treatment Bone health and treatments

UN Sustainable Development Goals

Zero hunger

Publication Details

Published in: New England Journal of Medicine

Volume 351, Issue 15, pp. 1502-1512

DOI: 10.1056/nejmoa040720

Field-Weighted Citation Impact: 179.22