High‐Dose Daptomycin for Treatment of Complicated Gram‐Positive Infections: A Large, Multicenter, Retrospective Study

2011133 citationsJournal Article

Authors

Ravina Kullar · Eugene Applebaum College of Pharmacy and Health Sciences

Susan L. Davis · Eugene Applebaum College of Pharmacy and Health Sciences

Donald P. Levine

Jing Zhao · Detroit Medical Center

Christopher W. Crank · Detroit Historical Society

John Segreti

George Sakoulas · University of California, San Diego

Sara E. Cosgrove

Abstract

Daptomycin dosages of 8 mg/kg/day or greater may be safe and effective in patients with complicated gram-positive infections. Further clinical studies are warranted.

Topics & Keywords

Antimicrobial Resistance in Staphylococcus Bacterial Identification and Susceptibility Testing Infective Endocarditis Diagnosis and Management

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy

Volume 31, Issue 6, pp. 527-536

DOI: 10.1592/phco.31.6.527

Field-Weighted Citation Impact: 9.39