Finding disease specific alterations in the co-expression of genes

2004155 citationsJournal Article

Authors

Dennis Kostka · Max Planck Institute for Molecular Genetics

Rainer Spang · Max Planck Institute for Molecular Genetics

Abstract

We introduce a score for differential co-expression and suggest a computationally efficient algorithm for finding high scoring sets of genes. The use of our novel method is demonstrated in the context of simulations and on real expression data from a clinical study.

Topics & Keywords

Gene expression and cancer classification Bioinformatics and Genomic Networks Genomics and Chromatin Dynamics

Publication Details

Published in: Bioinformatics

Volume 20, Issue suppl_1, pp. i194-i199

DOI: 10.1093/bioinformatics/bth909

Field-Weighted Citation Impact: 1.44

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Finding disease specific alterations in the co-expression of genes

Authors

Abstract

Topics & Keywords

Publication Details