Ischaemic preconditioning-regulated miR-21 protects heart against ischaemia/reperfusion injury via anti-apoptosis through its target PDCD4

2010331 citationsJournal Articlebronze Open Access

Authors

Yan Cheng · Rutgers New Jersey Medical School

Ping Zhu · Guangdong General Hospital

H. J. Yang · Rutgers New Jersey Medical School

Xiaodong Liu · Rutgers New Jersey Medical School

Shuohui Dong · Rutgers New Jersey Medical School

X. Wang · Rutgers New Jersey Medical School

Byung‐Yeol Chun

Abstract

The results suggest that miRNAs are involved in IP-mediated cardiac protection. Identifying the roles of IP-regulated miRNAs in cardiac protection may provide novel therapeutic and preventive targets for ischaemic heart disease.

Topics & Keywords

MicroRNA in disease regulation Circular RNAs in diseases Cardiac Ischemia and Reperfusion

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Cardiovascular Research

Volume 87, Issue 3, pp. 431-439

DOI: 10.1093/cvr/cvq082

Field-Weighted Citation Impact: 10.62