Whole-Blood Thrombin Generation Monitored with a Calibrated Automated Thrombogram-Based Assay

2012126 citationsJournal Articlebronze Open Access

Authors

Marisa Ninivaggi · Maastricht University

Rafael Apitz‐Castro · Maastricht University

Yesim Dargaud · Hôpital Edouard Herriot

Bas de Laat · Synapse (Netherlands)

H.C. Hemker · Synapse (Netherlands)

Theo Lindhout · Synapse (Netherlands)

Abstract

We have developed a reliable method to measure TG in whole blood. The assay can be performed with a drop of blood and may provide a useful measurement of TG under more physiological conditions than plasma.

Topics & Keywords

Blood Coagulation and Thrombosis Mechanisms Hemophilia Treatment and Research Platelet Disorders and Treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Chemistry

Volume 58, Issue 8, pp. 1252-1259

DOI: 10.1373/clinchem.2012.184077

Field-Weighted Citation Impact: 6.63