Researchclopedia

Research Researchers Institutions Topics Submit About

Command Palette

Search for a command to run...

Researchclopedia

Research Researchers Institutions About

© 2026 Researchclopedia. Powered by OpenAlex under CC0 license.

Back to research

Sildenafil Citrate Therapy for Pulmonary Arterial Hypertension

20052,456 citationsletterbronze Open Access

Authors

Nazzareno Galiè · University of Bologna

Hossein Ardeschir Ghofrani · University of Giessen

Robyn J. Barst · NewYork–Presbyterian Hospital

Lewis J. Rubin · University of California, San Diego

David B. Badesch · University of Colorado Health

Thomas R. Fleming · University of Washington

Abstract

Sildenafil improves exercise capacity, WHO functional class, and hemodynamics in patients with symptomatic pulmonary arterial hypertension.

Topics & Keywords

Pulmonary Hypertension Research and Treatments Cardiovascular Issues in Pregnancy Heart Failure Treatment and Management

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 353, Issue 20, pp. 2148-2157

DOI: 10.1056/nejmoa050010

Field-Weighted Citation Impact: 110.58

Sildenafil Citrate Therapy for Pulmonary Arterial Hypertension | Researchclopedia

Tamiza Parpia · Pfizer (United Kingdom)

Gary Burgess · Pfizer (United Kingdom)

Angelo Branzi · University of Bologna

Friedrich Grimminger · University of Giessen

Gérald Simonneau · Hôpital Antoine-Béclère