Assessment of Response to Lithium Maintenance Treatment in Bipolar Disorder: A Consortium on Lithium Genetics (ConLiGen) Report

2013419 citationsJournal Articlegold Open Access

Authors

Mirko Manchia · Dalhousie University

Mazda Adli · Charité - Universitätsmedizin Berlin

Nirmala Akula · National Institute of Mental Health

Raffaella Ardau · University of Cagliari

Jean-Michel Aubry · Hôpital Beau-Séjour

Lena Backlund · Karolinska Institutet

Cláudio E. M. Banzato ·

Abstract

We identified two definitions of lithium response, one dichotomous and the other continuous, with moderate to substantial inter-rater agreement and reliability. Accurate phenotypic measurement of lithium response is crucial for the ongoing ConLiGen pharmacogenomic study.

Topics & Keywords

Bipolar Disorder and Treatment Genetics and Neurodevelopmental Disorders Adolescent and Pediatric Healthcare

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: PLoS ONE

Volume 8, Issue 6, pp. e65636-e65636

DOI: 10.1371/journal.pone.0065636

Field-Weighted Citation Impact: 21.45