Correlation of Alcohol Craving With Striatal Dopamine Synthesis Capacity and D2/3 Receptor Availability: A Combined [18F]DOPA and [18F]DMFP PET Study in Detoxified Alcoholic Patients

2005279 citationsJournal Article

Authors

Andreas Heinz · Central Institute of Mental Health

Thomas Siessmeier

Mathias Schreckenberger

Abstract

Simultaneous assay by PET of pre- and postsynaptic markers of dopamine neurotransmission indicated that a striatal dopamine deficit correlated with alcohol craving, which was associated with a high relapse risk.

Topics & Keywords

Neurotransmitter Receptor Influence on Behavior Neuroscience and Neuropharmacology Research Functional Brain Connectivity Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: American Journal of Psychiatry

Volume 162, Issue 8, pp. 1515-1520

DOI: 10.1176/appi.ajp.162.8.1515

Field-Weighted Citation Impact: 4.33

Command Palette

Correlation of Alcohol Craving With Striatal Dopamine Synthesis Capacity and D<sub>2/3</sub> Receptor Availability: A Combined [<sup>18</sup>F]DOPA and [<sup>18</sup>F]DMFP PET Study in Detoxified Alcoholic Patients

Authors

Abstract

Topics & Keywords

UN Sustainable Development Goals

Publication Details