High Prevalence of Hereditary Cancer Syndromes in Adolescents and Young Adults With Colorectal Cancer

2015249 citationsJournal Article

Authors

Maureen E. Mork · The University of Texas MD Anderson Cancer Center

Y. Nancy You · The University of Texas MD Anderson Cancer Center

Binwu Ying · The University of Texas MD Anderson Cancer Center

Sarah A. Bannon · The University of Texas MD Anderson Cancer Center

Patrick M. Lynch · The University of Texas MD Anderson Cancer Center

Miguel A. Rodrı́guez-Bigas · The University of Texas MD Anderson Cancer Center

Abstract

We conclude that patients diagnosed with CRC at age 35 years or younger should receive genetic counseling regardless of their family history and phenotype.

Topics & Keywords

Genetic factors in colorectal cancer DNA Repair Mechanisms BRCA gene mutations in cancer

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Clinical Oncology

Volume 33, Issue 31, pp. 3544-3549

DOI: 10.1200/jco.2015.61.4503

Field-Weighted Citation Impact: 11.76