Disuse Impairs the Muscle Protein Synthetic Response to Protein Ingestion in Healthy Men

2013174 citationsJournal Articlegreen Open Access

Authors

Benjamin T. Wall

Tim Snijders

Joan M. Senden

Chris L. P. Ottenbros · Maastricht University

Annemie P. Gijsen · Maastricht University

Lex B. Verdijk

Luc J. C. van Loon

Abstract

A short period of muscle disuse impairs the muscle protein synthetic response to dietary protein intake in vivo in healthy young men. Thus, anabolic resistance to protein ingestion contributes significantly to the loss of muscle mass that is observed during disuse.

Topics & Keywords

Muscle metabolism and nutrition Muscle Physiology and Disorders Sports Performance and Training

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Journal of Clinical Endocrinology & Metabolism

Volume 98, Issue 12, pp. 4872-4881

DOI: 10.1210/jc.2013-2098

Field-Weighted Citation Impact: 6.04