Inhibition of Arthritis in the Lewis Rat by Apolipoprotein A-I and Reconstituted High-Density Lipoproteins

201343 citationsJournal Articlebronze Open Access

Authors

Ben J. Wu · University of Sydney

Kwok Leung Ong · University of Sydney

Sudichhya Shrestha · University of Sydney

Kang Chen · University of Sydney

Fatiha Tabet · University of Sydney

Philip J. Barter · University of Sydney

Kerry‐Anne Rye ·

Abstract

Apolipoprotein A-I and reconstituted HDLs attenuate PG-PS-induced arthritis in the rat. Studies in human monocyte-derived macrophages indicate that this benefit may be because of the inhibition of toll-like receptor 2 expression and decreased nuclear factor-κB activation in macrophages.

Topics & Keywords

Lipoproteins and Cardiovascular Health Peroxisome Proliferator-Activated Receptors Adipokines, Inflammation, and Metabolic Diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Arteriosclerosis Thrombosis and Vascular Biology

Volume 34, Issue 3, pp. 543-551

DOI: 10.1161/atvbaha.113.302832

Field-Weighted Citation Impact: 4.07