mRNA/microRNA gene expression profile in microsatellite unstable colorectal cancer

2007284 citationsJournal Articlegold Open Access

Authors

Giovanni Lanza · University of Ferrara

Manuela Ferracin · University of Ferrara

Roberta Gafà · University of Ferrara

Angelo Veronese · University of Ferrara

Riccardo Spizzo · University of Ferrara

Flavia Pichiorri · The Ohio State University

Chang‐Gong Liu ·

Abstract

This is the first report that indicates the existence of differences in miRNA expression between MSS versus MSI-H colorectal cancers. In addition, the work suggests that the combination of mRNA/miRNA expression signatures may represent a general approach for improving bio-molecular classification of human cancer.

Topics & Keywords

MicroRNA in disease regulation Genetic factors in colorectal cancer RNA modifications and cancer

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Molecular Cancer

Volume 6, Issue 1, pp. 54-54

DOI: 10.1186/1476-4598-6-54

Field-Weighted Citation Impact: 9.18