Highly Diastereo- and Enantioselective Intramolecular Amidation of Saturated CH Bonds Catalyzed by Ruthenium Porphyrins

2002280 citationsJournal Article

Authors

Jiang-Lin Liang · University of Hong Kong

Jie-Sheng Huang · University of Hong Kong

Abstract

Virtually complete diastereoselectivity is observed in the intramolecular amidation of saturated CH bonds, catalyzed by the ruthenium porphyrin catalyst 1 or 2. Reactions of sulfamate esters with PhI(OAc)2 in the presence of 1 or 2 afforded cyclic sulfamidates in up to 87 % ee.

Topics & Keywords

Synthesis and Catalytic Reactions Asymmetric Hydrogenation and Catalysis Chemical Synthesis and Analysis

UN Sustainable Development Goals

Clean water and sanitation

Publication Details

Published in: Angewandte Chemie International Edition

Volume 41, Issue 18, pp. 3465-3468

DOI: 10.1002/1521-3773(20020916)41:18<3465::aid-anie3465>3.0.co;2-d

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